Acid Rock Drainage In the search for bioactive metabolites, natural products chemists traditionally explored easily accessible terrestrial environments. However, by the 1990s, we realized that all of the “low hanging fruit” had been picked and natural product rediscovery rates increased. As such, underexplored environments, such as acid rock drainage, are now being explored for new bioactive compounds.

Antarctic Desert Understanding the molecular ecology of an environment is essential for monitoring and predicting the effects of a rapidly changing biosphere. Microbial secondary metabolites are diverse molecules that mediate synergistic and antagonistic microbial interactions, and therefore play essential roles in defining microbial community structure. These low molecular weight organic molecules are molecular forms ...